A rare report of acute severe dyspnea, hemodynamic instability and cardiac arrest following crystal methamphetamine inhalation

Gholami, Farhad and Hosseini, Seyed Hamzeh and Ahmadi, Amirhossein and Nabati, Maryam (2019) A rare report of acute severe dyspnea, hemodynamic instability and cardiac arrest following crystal methamphetamine inhalation. Pharmaceutical and Biomedical Research, 5 (2). pp. 23-26.

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Official URL: http://pbr.mazums.ac.ir/article-1-226-en.html

Abstract

Abuse of amphetamine-like stimulants is a global problem. Myocardial infarction is a rarely reported complication of amphetamine abuse. Herein, we describe a 42-year-old man presented at the emergency department with complaints of severe dyspnea following ice inhalation without previous history of dyspnea. Within the first hour and a half after admission, the patient was initially treated by nasal oxygen and bronchodilator aminophylline. However, the patient did not respond to the initial treatment for severe dyspnea. Then, the patient developed loss of consciousness, ventricular fibrillation, cardiac arrest, and hemodynamic instability. Cardiopulmonary resuscitation (CPR) was immediately initiated. The patient was intubated, mechanically ventilated and administered synchronized electrical shock for five times (200-360 J) along with amiodarone (300 mg intravenously (IV), stat, then 1 mg/minute IV infusion for 6 hours and then 0.5 mg/minute for 18 hours) to treat the ventricular fibrillation. The arrhythmia was subsequently controlled, and normal sinus rhythm was resumed. Two hours later, the patient's condition was improved and he was extubated. After two days, when the patient got stable, the echocardiography after cardiac arrest performed and it was completely normal.

Item Type: Article
Uncontrolled Keywords: crystal methamphetamine, severe dyspnea, cardiac arrest, ventricular fibrillation, hemodynamic instability
Depositing User: Unnamed user with email eprints@mazums.ac.ir
Date Deposited: 03 Jul 2019 07:24
Last Modified: 03 Jul 2019 07:24
URI: http://eprints.mazums.ac.ir/id/eprint/4631

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