The Comparison of Priming with Pancrunium and Atracurium in the Speed of Providing Adequate Neuromuscular Blockade for Tracheal Intubating

Parish, M and Mahmoodpoor, A and Gharahdaghi, N and Sanaie, S (2007) The Comparison of Priming with Pancrunium and Atracurium in the Speed of Providing Adequate Neuromuscular Blockade for Tracheal Intubating. Journal of Mazandaran University of Medical Sciences, 17 (58). pp. 37-42.

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Official URL: http://jmums.mazums.ac.ir/article-1-211-en.html

Abstract

Background and purpose: Neuromuscular relaxants are one group of the important drugs in providing good condition for tracheal intubation and operation. Rapid intubation is needed in most situations. Also, most of non- depolarizing relaxants almost have long onset time. We compared the priming with pancrunium and atracurium in providing good and rapid relaxation for tracheal intubation. Materials and Methods: In this prospective study, 65 patients with ASA class I, II were randomized into two groups. Group A received pancrunium and group B received atracurium. Primimg dose was injected as 20 of total dose of relaxant. Twitching response was measured with peripheral nerve stimulator. Intubation was done when 80 of the twitching response disappeared. The time of total disappearance of twitching response was also recorded. Results: The mean time for the injection of the first dose of relaxant until the time of intubation was 94.47 seconds in group A and 142.9 seconds in group B, which were significantly different (P<0/01). If intubation until the time of twitch response is detained, the time gap of group A will again be less than group B (P<0/01). Conclusion: In priming technique, the time of tracheal intubation with pancrunium is significantly less than atracurium. So, considering the patient's condition and the need for rapid relaxation, pancrunium could be is a better relaxant than atracurium.

Item Type: Article
Uncontrolled Keywords: Pancrunium, Atracurium, Priming, Tracheal intubation
Depositing User: Unnamed user with email eprints@mazums.ac.ir
Date Deposited: 04 Jan 2018 17:52
Last Modified: 04 Jan 2018 17:52
URI: http://eprints.mazums.ac.ir/id/eprint/3179

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