Investigating the Relationship between Eosinophilia and Coronary Artery Disease in Patients with Kawasaki Disease

Rezai, Mohhamad Sadegh and Shokohi, Leila and Saffar, Mohhad Jafar and Zeinali, Aida and Abaskhanian, Ali (2012) Investigating the Relationship between Eosinophilia and Coronary Artery Disease in Patients with Kawasaki Disease. Journal of Mazandaran University of Medical Sciences, 22 (88). pp. 10-16.

Full text not available from this repository.
Official URL: http://jmums.mazums.ac.ir/article-1-987-en.html

Abstract

Background and purpose: Kawasaki disease (KD) is an acute vasculitis in children. Studies indicated different relationships between eosinophilia and coronary artery disease (CAD). This study was done to assess the possible relationship between eosinophilia and coronary artery disease. Materials and methods: This descriptive study was carried out during 13 years on 61 children with Kawasaki disease who were admitted to Sina Referral Hospital. They were assessed regarding eosinophilia and coronary artery diseases. Data was evaluated by Fisher exact and t-test. Results: The research population included 61 patients of whom 33 (54) were male and 28 (46) were female with the mean age of 36.56 ± 23 months. Among the patients 85 were >5 years of age and eosinophilia was found in 28 cases (45.9) and five patients (14.8) were diagnosed with coronary artery disease. This disease was observed in 25 suffering from eosinophilia and in 6 of the cases without eosinophilia. However, there was no association among gender, eosinophilia and coronary artery disease. Also, no significant difference was found between age groups. Conclusion: Eosinophilia was not a risk factor or protective factor for CAD. However, the exact relationship could be determined if further multicentre studies are carried out.

Item Type: Article
Uncontrolled Keywords: Kawasaki disease, coronary artery, eosinophilia, pediatrics
Depositing User: Unnamed user with email eprints@mazums.ac.ir
Date Deposited: 04 Jan 2018 16:49
Last Modified: 04 Jan 2018 16:49
URI: http://eprints.mazums.ac.ir/id/eprint/2376

Actions (login required)

View Item View Item