Prevalence of β-lactamase Enzyme in Isolated Bacteria in Patients with Nosocomial Infections, Skin and Wound infections from Imam Khomeini Hospital of Sari Province, 2010

Pourhajibagher, Maryam and Nasrollahi, Mohtaram and Eini, Mohamad Iman and RahimiEsboei, Bahm (2014) Prevalence of β-lactamase Enzyme in Isolated Bacteria in Patients with Nosocomial Infections, Skin and Wound infections from Imam Khomeini Hospital of Sari Province, 2010. Journal of Mazandaran University of Medical Sciences, 23 (1). pp. 261-265.

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Official URL: http://jmums.mazums.ac.ir/article-1-3628-en.html

Abstract

Background and purpose: Hospital infections are common throughout the world. Antibiotic resistance is caused after infectious diseases and hospital infections. Considering the importance of hospital infection and bacteria resistant to antibiotics, this study aimed at investigating the prevalence of β-lactamase enzymes in bacteria isolated from nosocomial infections. Material and Methods: Fifty samples of skin infections and 50 samples from wounds were collected from Imam Khomeini Hospital in Sari and were studied using biochemical tests and identification of beta-lactamase. Results: In this study, 180 organisms were isolated from 100 samples of skin infections and wound. The production of β-lactamase enzymes by acidimetric method in these samples showed that 26 samples (14.4) were β-lactamase positive and 154 samples (85.6) were β-lactamase negative and gram positive cocci and bacilli. Conclusion: β-lactamase positive bacteria not only increase the risk of nosocomial infections, especially skin infections in people with weakened immune systems but also make them resistant to β- lactam group of antibiotics.

Item Type: Article
Uncontrolled Keywords: Skin Infections, Ulcers infection, β-lactamase, antibiotics
Depositing User: Unnamed user with email eprints@mazums.ac.ir
Date Deposited: 04 Jan 2018 18:19
Last Modified: 04 Jan 2018 18:19
URI: http://eprints.mazums.ac.ir/id/eprint/2259

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